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Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation
BACKGROUND: Breast cancer formation is associated with frequent changes in DNA methylation but the extent of very early alterations in DNA methylation and the biological significance of cancer-associated epigenetic changes need further elucidation. METHODS: Pyrosequencing was done on bisulfite-treat...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625569/ https://www.ncbi.nlm.nih.gov/pubmed/26510686 http://dx.doi.org/10.1186/s12885-015-1777-9 |