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Evolution of an archaeal virus nucleocapsid protein from the CRISPR-associated Cas4 nuclease

ABSTRACT: Many proteins of viruses infecting hyperthermophilic Crenarchaeota have no detectable homologs in current databases, hampering our understanding of viral evolution. We used sensitive database search methods and structural modeling to show that a nucleocapsid protein (TP1) of Thermoproteus...

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Detalles Bibliográficos
Autores principales: Krupovic, Mart, Cvirkaite-Krupovic, Virginija, Prangishvili, David, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625639/
https://www.ncbi.nlm.nih.gov/pubmed/26514828
http://dx.doi.org/10.1186/s13062-015-0093-2