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MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated

BACKGROUND: Ιn multiple sclerosis (MS), axonal damage leads to permanent neurological disabilities and the spreading of the autoimmune response to axonal antigens is implicated in disease progression. Experimental autoimmune encephalomyelitis (EAE) provides an animal model that mimics MS. Using diff...

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Detalles Bibliográficos
Autores principales: Flytzani, Sevasti, Guerreiro-Cacais, Andre Ortlieb, N’diaye, Marie, Lindner, Maren, Linington, Christopher, Meinl, Edgar, Stridh, Pernilla, Jagodic, Maja, Olsson, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625640/
https://www.ncbi.nlm.nih.gov/pubmed/26511327
http://dx.doi.org/10.1186/s12974-015-0417-2