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Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data

BACKGROUND/AIMS: Pediatric inflammatory bowel disease (IBD) has been increasing worldwide. The characteristics of pediatric-onset IBD have mainly been reported in Western countries. We investigated the clinical characteristics of pediatric IBD in Korea and compared these with the data from the 5-yea...

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Autores principales: Ah Lee, Hyeon, Suk, Jung Yoon, Choi, Sung Youn, Kim, Eun Ran, Kim, Young-Ho, Lee, Chang Kyun, Huh, Kyu Chan, Lee, Kang Moon, Park, Dong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625705/
https://www.ncbi.nlm.nih.gov/pubmed/25963086
http://dx.doi.org/10.5009/gnl14338
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author Ah Lee, Hyeon
Suk, Jung Yoon
Choi, Sung Youn
Kim, Eun Ran
Kim, Young-Ho
Lee, Chang Kyun
Huh, Kyu Chan
Lee, Kang Moon
Park, Dong Il
author_facet Ah Lee, Hyeon
Suk, Jung Yoon
Choi, Sung Youn
Kim, Eun Ran
Kim, Young-Ho
Lee, Chang Kyun
Huh, Kyu Chan
Lee, Kang Moon
Park, Dong Il
author_sort Ah Lee, Hyeon
collection PubMed
description BACKGROUND/AIMS: Pediatric inflammatory bowel disease (IBD) has been increasing worldwide. The characteristics of pediatric-onset IBD have mainly been reported in Western countries. We investigated the clinical characteristics of pediatric IBD in Korea and compared these with the data from the 5-year European multicenter study of children with new-onset IBD (EUROKIDS registry). METHODS: Children who were diagnosed with IBD between July 1987 and January 2012 were investigated at five Korean university hospitals. Their clinical characteristics were retrospectively evaluated by medical record review. The results were compared with the EUROKIDS data. RESULTS: A total of 30 children with Crohn’s disease (CD) and 33 children with ulcerative colitis (UC) were enrolled. In comparison with the EUROKIDS group, Korean pediatric IBD patients showed a male predominance (86.7% vs 59.2%, p=0.002 in CD; 75.8% vs 50%, p=0.003 in UC). Korean pediatric CD patients had a higher prevalence of terminal ileal disease (36.7% vs 16.3%, p=0.004) and perianal disease (33.3% vs 8.2%, p<0.001) than patients in the EUROKIDS group. Korean pediatric UC patients had a higher prevalence of proctitis than patients in the EUROKIDS group. CONCLUSIONS: Our results suggest that the characteristics of Korean pediatric IBD patients and European pediatric IBD patients may be different.
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spelling pubmed-46257052015-11-01 Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data Ah Lee, Hyeon Suk, Jung Yoon Choi, Sung Youn Kim, Eun Ran Kim, Young-Ho Lee, Chang Kyun Huh, Kyu Chan Lee, Kang Moon Park, Dong Il Gut Liver Original Article BACKGROUND/AIMS: Pediatric inflammatory bowel disease (IBD) has been increasing worldwide. The characteristics of pediatric-onset IBD have mainly been reported in Western countries. We investigated the clinical characteristics of pediatric IBD in Korea and compared these with the data from the 5-year European multicenter study of children with new-onset IBD (EUROKIDS registry). METHODS: Children who were diagnosed with IBD between July 1987 and January 2012 were investigated at five Korean university hospitals. Their clinical characteristics were retrospectively evaluated by medical record review. The results were compared with the EUROKIDS data. RESULTS: A total of 30 children with Crohn’s disease (CD) and 33 children with ulcerative colitis (UC) were enrolled. In comparison with the EUROKIDS group, Korean pediatric IBD patients showed a male predominance (86.7% vs 59.2%, p=0.002 in CD; 75.8% vs 50%, p=0.003 in UC). Korean pediatric CD patients had a higher prevalence of terminal ileal disease (36.7% vs 16.3%, p=0.004) and perianal disease (33.3% vs 8.2%, p<0.001) than patients in the EUROKIDS group. Korean pediatric UC patients had a higher prevalence of proctitis than patients in the EUROKIDS group. CONCLUSIONS: Our results suggest that the characteristics of Korean pediatric IBD patients and European pediatric IBD patients may be different. Editorial Office of Gut and Liver 2015-11 2015-05-13 /pmc/articles/PMC4625705/ /pubmed/25963086 http://dx.doi.org/10.5009/gnl14338 Text en Copyright © 2015 by The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ah Lee, Hyeon
Suk, Jung Yoon
Choi, Sung Youn
Kim, Eun Ran
Kim, Young-Ho
Lee, Chang Kyun
Huh, Kyu Chan
Lee, Kang Moon
Park, Dong Il
Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
title Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
title_full Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
title_fullStr Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
title_full_unstemmed Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
title_short Characteristics of Pediatric Inflammatory Bowel Disease in Korea: Comparison with EUROKIDS Data
title_sort characteristics of pediatric inflammatory bowel disease in korea: comparison with eurokids data
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625705/
https://www.ncbi.nlm.nih.gov/pubmed/25963086
http://dx.doi.org/10.5009/gnl14338
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