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The effect of early surgery after hip fracture on 1-year mortality

BACKGROUND: Hip fracture injuries are identified as one of the most serious healthcare problems affecting older people. Many studies have explored the associations among patient characteristics, treatment processes, time to surgery and various outcomes in patients hospitalized for hip fracture. The...

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Autores principales: Colais, Paola, Di Martino, Mirko, Fusco, Danilo, Perucci, Carlo Alberto, Davoli, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625722/
https://www.ncbi.nlm.nih.gov/pubmed/26510919
http://dx.doi.org/10.1186/s12877-015-0140-y
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author Colais, Paola
Di Martino, Mirko
Fusco, Danilo
Perucci, Carlo Alberto
Davoli, Marina
author_facet Colais, Paola
Di Martino, Mirko
Fusco, Danilo
Perucci, Carlo Alberto
Davoli, Marina
author_sort Colais, Paola
collection PubMed
description BACKGROUND: Hip fracture injuries are identified as one of the most serious healthcare problems affecting older people. Many studies have explored the associations among patient characteristics, treatment processes, time to surgery and various outcomes in patients hospitalized for hip fracture. The objective of the present study is to evaluate the difference in 1-year mortality after hip fracture between patients undergoing early surgery (within 2 days) and patients undergoing delayed surgery in Italy. METHODS: Observational, retrospective study based on the Hospital Information System (HIS). This cohort study included patients aged 65 years and older who were residing in Italy and were admitted to an acute care hospital for a hip fracture between 1 January 2007 and 31 December 2012. A multivariate Cox regression analysis was used to assess the effect of early surgery on the likelihood of 1-year mortality after hip fracture, adjusting for risk factors that could affect the outcome under study. The absolute number of deaths prevented by exposure to early surgery was calculated. RESULTS: We studied a total of 405,037 admissions for hip fracture. Patients who underwent surgery within 2 days had lower 1-year mortality compared to those who waited for surgery more than 2 days (Hazard Ratios -HR-: 0.83; 95 % CI: 0.82–0.85). The number of deaths prevented by the exposure to early surgery was 5691. CONCLUSIONS: This study is the first to evaluate the association between time to surgery and 1-year mortality for all Italian elderly patients hospitalized for hip fracture. The study confirmed the previous reports on the association between delayed surgery and increased mortality and complication rates in elderly patients admitted for hip fracture. Our data support the notion that deviating from surgical guidelines in hip fracture is costly, in terms of both human life and excess hospital stay. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12877-015-0140-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-46257222015-10-30 The effect of early surgery after hip fracture on 1-year mortality Colais, Paola Di Martino, Mirko Fusco, Danilo Perucci, Carlo Alberto Davoli, Marina BMC Geriatr Research Article BACKGROUND: Hip fracture injuries are identified as one of the most serious healthcare problems affecting older people. Many studies have explored the associations among patient characteristics, treatment processes, time to surgery and various outcomes in patients hospitalized for hip fracture. The objective of the present study is to evaluate the difference in 1-year mortality after hip fracture between patients undergoing early surgery (within 2 days) and patients undergoing delayed surgery in Italy. METHODS: Observational, retrospective study based on the Hospital Information System (HIS). This cohort study included patients aged 65 years and older who were residing in Italy and were admitted to an acute care hospital for a hip fracture between 1 January 2007 and 31 December 2012. A multivariate Cox regression analysis was used to assess the effect of early surgery on the likelihood of 1-year mortality after hip fracture, adjusting for risk factors that could affect the outcome under study. The absolute number of deaths prevented by exposure to early surgery was calculated. RESULTS: We studied a total of 405,037 admissions for hip fracture. Patients who underwent surgery within 2 days had lower 1-year mortality compared to those who waited for surgery more than 2 days (Hazard Ratios -HR-: 0.83; 95 % CI: 0.82–0.85). The number of deaths prevented by the exposure to early surgery was 5691. CONCLUSIONS: This study is the first to evaluate the association between time to surgery and 1-year mortality for all Italian elderly patients hospitalized for hip fracture. The study confirmed the previous reports on the association between delayed surgery and increased mortality and complication rates in elderly patients admitted for hip fracture. Our data support the notion that deviating from surgical guidelines in hip fracture is costly, in terms of both human life and excess hospital stay. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12877-015-0140-y) contains supplementary material, which is available to authorized users. BioMed Central 2015-10-28 /pmc/articles/PMC4625722/ /pubmed/26510919 http://dx.doi.org/10.1186/s12877-015-0140-y Text en © Colais et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Colais, Paola
Di Martino, Mirko
Fusco, Danilo
Perucci, Carlo Alberto
Davoli, Marina
The effect of early surgery after hip fracture on 1-year mortality
title The effect of early surgery after hip fracture on 1-year mortality
title_full The effect of early surgery after hip fracture on 1-year mortality
title_fullStr The effect of early surgery after hip fracture on 1-year mortality
title_full_unstemmed The effect of early surgery after hip fracture on 1-year mortality
title_short The effect of early surgery after hip fracture on 1-year mortality
title_sort effect of early surgery after hip fracture on 1-year mortality
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625722/
https://www.ncbi.nlm.nih.gov/pubmed/26510919
http://dx.doi.org/10.1186/s12877-015-0140-y
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