Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis

BACKGROUND: The failure to mount an effective DNA damage response to repair UV induced cyclobutane pyrimidine dimers (CPDs) results in an increased propensity to develop cutaneous squamous cell carcinoma (cSCC). High-risk patient groups, such as organ transplant recipients (OTRs) frequently exhibit...

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Detalles Bibliográficos
Autores principales: Hufbauer, Martin, Cooke, James, van der Horst, Gijsbertus T. J., Pfister, Herbert, Storey, Alan, Akgül, Baki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625724/
https://www.ncbi.nlm.nih.gov/pubmed/26511842
http://dx.doi.org/10.1186/s12943-015-0453-7

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