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Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data
BACKGROUND: Recently, rapid improvements in technology and decrease in sequencing costs have made RNA-Seq a widely used technique to quantify gene expression levels. Various normalization approaches have been proposed, owing to the importance of normalization in the analysis of RNA-Seq data. A compa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625728/ https://www.ncbi.nlm.nih.gov/pubmed/26511205 http://dx.doi.org/10.1186/s12859-015-0778-7 |