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Decline of FOXN1 gene expression in human thymus correlates with age: possible epigenetic regulation
BACKGROUND: Thymic involution is thought to be an important factor of age related immunodeficiency. Understanding the molecular mechanisms of human thymic senescence may lead to the discovery of novel therapeutic approaches aimed at the reestablishment of central and peripheral T cell repertoire. RE...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625732/ https://www.ncbi.nlm.nih.gov/pubmed/26516334 http://dx.doi.org/10.1186/s12979-015-0045-9 |