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Physiome-on-a-Chip: The Challenge of “Scaling” in Design, Operation, and Translation of Microphysiological Systems
Scaling of a microphysiological system (MPS) or physiome-on-a-chip is arguably two interrelated, modeling-based activities: on-platform scaling and in vitro-in vivo translation. This dual approach reduces the need to perfectly rescale and mimic in vivo physiology, an aspiration that is both extremel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley & Sons, Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625858/ https://www.ncbi.nlm.nih.gov/pubmed/26535154 http://dx.doi.org/10.1002/psp4.12042 |