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Correlation between mutations and mRNA expression of APC and MUTYH genes: new insight into hereditary colorectal polyposis predisposition
BACKGROUND: Transcript dosage imbalance may influence the transcriptome. To gain insight into the role of altered gene expression in hereditary colorectal polyposis predisposition, in the present study we analyzed absolute and allele-specific expression (ASE) of adenomatous polyposis coli (APC) and...
Autores principales: | Aceto, Gitana Maria, Fantini, Fabiana, De Iure, Sabrina, Di Nicola, Marta, Palka, Giandomenico, Valanzano, Rosa, Di Gregorio, Patrizia, Stigliano, Vittoria, Genuardi, Maurizio, Battista, Pasquale, Cama, Alessandro, Curia, Maria Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625907/ https://www.ncbi.nlm.nih.gov/pubmed/26511139 http://dx.doi.org/10.1186/s13046-015-0244-4 |
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