Negative studies are helpful to compute the specificity of diagnostic tests: measuring Trypanosoma cruzi seroprevalence in Guanajuato, Mexico

BACKGROUND: Publishing negative seroprevalence studies not only helps to have more accurate seroprevalence estimates but also allows calculating the specificity of the diagnostic tests used. We performed a population-based Trypanosoma cruzi seroprevalence survey in a community in central Mexico. RES...

Descripción completa

Detalles Bibliográficos
Autores principales: Padilla-Raygoza, Nicolás, Gamboa-León, Rubí, Ramirez-Sierra, Maria Jesus, Dumonteil, Eric, Buekens, Pierre, Ruiz-Paloalto, Ma Laura, Diaz-Guerrero, Rosalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625936/
https://www.ncbi.nlm.nih.gov/pubmed/26510987
http://dx.doi.org/10.1186/s13104-015-1612-z
Descripción
Sumario:BACKGROUND: Publishing negative seroprevalence studies not only helps to have more accurate seroprevalence estimates but also allows calculating the specificity of the diagnostic tests used. We performed a population-based Trypanosoma cruzi seroprevalence survey in a community in central Mexico. RESULTS: We surveyed 204 women and children and collected blood by finger prick. We performed rapid tests (Stat-Pak, Chembio, Inc., Medford, New York) and recombinant Chagas ELISA tests v3.0 (Wiener, Rosario, Argentina). All rapid tests and all ELISA tests were negative. CONCLUSION: The rapid test had 100 % of specificity compared to the ELISA.

Ejemplares similares