Counterintuitive DNA Sequence Dependence in Supercoiling-Induced DNA Melting

The metabolism of DNA in cells relies on the balance between hybridized double-stranded DNA (dsDNA) and local de-hybridized regions of ssDNA that provide access to binding proteins. Traditional melting experiments, in which short pieces of dsDNA are heated up until the point of melting into ssDNA, h...

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Detalles Bibliográficos
Autores principales: Vlijm, Rifka, v.d. Torre, Jaco, Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625975/
https://www.ncbi.nlm.nih.gov/pubmed/26513573
http://dx.doi.org/10.1371/journal.pone.0141576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625975/
https://www.ncbi.nlm.nih.gov/pubmed/26513573
http://dx.doi.org/10.1371/journal.pone.0141576

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