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Counterintuitive DNA Sequence Dependence in Supercoiling-Induced DNA Melting
The metabolism of DNA in cells relies on the balance between hybridized double-stranded DNA (dsDNA) and local de-hybridized regions of ssDNA that provide access to binding proteins. Traditional melting experiments, in which short pieces of dsDNA are heated up until the point of melting into ssDNA, h...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625975/ https://www.ncbi.nlm.nih.gov/pubmed/26513573 http://dx.doi.org/10.1371/journal.pone.0141576 |