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APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction
Aging is the major risk factor for neurodegenerative diseases such as Alzheimer's disease, but little is known about the processes that lead to age-related decline of brain structures and function. Here we use RNA-seq in combination with high resolution histological analyses to show that aging...
Autores principales: | Soto, Ileana, Graham, Leah C., Richter, Hannah J., Simeone, Stephen N., Radell, Jake E., Grabowska, Weronika, Funkhouser, W. Keith, Howell, Megan C., Howell, Gareth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626092/ https://www.ncbi.nlm.nih.gov/pubmed/26512759 http://dx.doi.org/10.1371/journal.pbio.1002279 |
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