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Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice

Gravity change affects many immunological systems. We investigated the effects of hypergravity (2G) on murine thymic cells. Exposure of mice to 2G for three days reduced the frequency of CD4(+)CD8(+) thymocytes (DP) and mature medullary thymic epithelial cells (mTECs), accompanied by an increment of...

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Detalles Bibliográficos
Autores principales: Tateishi, Ryosuke, Akiyama, Nobuko, Miyauchi, Maki, Yoshinaga, Riko, Sasanuma, Hiroki, Kudo, Takashi, Shimbo, Miki, Shinohara, Masahiro, Obata, Koji, Inoue, Jun-ichiro, Shirakawa, Masaki, Shiba, Dai, Asahara, Hiroshi, Yoshida, Nobuaki, Takahashi, Satoru, Morita, Hironobu, Akiyama, Taishin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626100/
https://www.ncbi.nlm.nih.gov/pubmed/26513242
http://dx.doi.org/10.1371/journal.pone.0141650