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Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice
Gravity change affects many immunological systems. We investigated the effects of hypergravity (2G) on murine thymic cells. Exposure of mice to 2G for three days reduced the frequency of CD4(+)CD8(+) thymocytes (DP) and mature medullary thymic epithelial cells (mTECs), accompanied by an increment of...
Autores principales: | Tateishi, Ryosuke, Akiyama, Nobuko, Miyauchi, Maki, Yoshinaga, Riko, Sasanuma, Hiroki, Kudo, Takashi, Shimbo, Miki, Shinohara, Masahiro, Obata, Koji, Inoue, Jun-ichiro, Shirakawa, Masaki, Shiba, Dai, Asahara, Hiroshi, Yoshida, Nobuaki, Takahashi, Satoru, Morita, Hironobu, Akiyama, Taishin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626100/ https://www.ncbi.nlm.nih.gov/pubmed/26513242 http://dx.doi.org/10.1371/journal.pone.0141650 |
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