Cargando…
New Isoform of Cardiac Myosin Light Chain Kinase and the Role of Cardiac Myosin Phosphorylation in α(1)-Adrenoceptor Mediated Inotropic Response
BACKGROUND & AIMS: Cardiac myosin light chain kinase (cMLCK) plays an obligatory role in maintaining the phosphorylation levels of regulatory myosin light chain (MLC2), which is thought to be crucial for regulation of cardiac function. To test this hypothesis, the role played by ventricular MLC2...
Autores principales: | Taniguchi, Masaya, Okamoto, Ryuji, Ito, Masaaki, Goto, Itaru, Fujita, Satoshi, Konishi, Katsuhisa, Mizutani, Hideo, Dohi, Kaoru, Hartshorne, David J., Itoh, Takeo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626101/ https://www.ncbi.nlm.nih.gov/pubmed/26512720 http://dx.doi.org/10.1371/journal.pone.0141130 |
Ejemplares similares
-
Inotropic interventions do not change the resting state of myosin motors during cardiac diastole
por: Caremani, Marco, et al.
Publicado: (2019) -
Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working stroke
por: Woody, Michael S., et al.
Publicado: (2018) -
Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemomechanical properties despite bearing the same myosin heavy chain isoform
por: Wang, Tianbang, et al.
Publicado: (2022) -
Effect of Myosin Isoforms on Cardiac Muscle Twitch of Mice, Rats and Humans
por: Prodanovic, Momcilo, et al.
Publicado: (2022) -
Nanosurfer assay dissects β-cardiac myosin and cardiac myosin-binding protein C interactions
por: Touma, Anja M., et al.
Publicado: (2022)