Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma

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Aberrant hedgehog signaling contributes to the development of various malignancies, including glioblastoma (GBM). However, the potential mechanism of hedgehog signaling in GBM migration and invasion has remained to be elucidated. The present study showed that enhanced hedgehog signaling by recombina...

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Detalles Bibliográficos
Autores principales: CHANG, LIANG, ZHAO, DAN, LIU, HUI-BIN, WANG, QIU-SHI, ZHANG, PING, LI, CHEN-LONG, DU, WEN-ZHONG, WANG, HONG-JUN, LIU, XING, ZHANG, ZHI-REN, JIANG, CHUAN-LU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626128/
https://www.ncbi.nlm.nih.gov/pubmed/26299938
http://dx.doi.org/10.3892/mmr.2015.4229

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