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IDH1(R132H) decreases the proliferation of U87 glioma cells through upregulation of microRNA-128a
Mutations in isocitrate dehydrogenase 1 (IDH1) are found in >70% of secondary glioblastomas and lower-grade gliomas (grades II–III). Among the numerous phenotypic differences between IDH1 mutant and wild-type glioma patients, the most salient is an improved survival rate for patients with a mutat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626131/ https://www.ncbi.nlm.nih.gov/pubmed/26324126 http://dx.doi.org/10.3892/mmr.2015.4241 |