Cargando…

IDH1(R132H) decreases the proliferation of U87 glioma cells through upregulation of microRNA-128a

Mutations in isocitrate dehydrogenase 1 (IDH1) are found in >70% of secondary glioblastomas and lower-grade gliomas (grades II–III). Among the numerous phenotypic differences between IDH1 mutant and wild-type glioma patients, the most salient is an improved survival rate for patients with a mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: NIE, QUAN-MIN, LIN, YING-YING, YANG, XI, SHEN, LIN, GUO, LIE-MEI, QUE, SHUANG-LIN, LI, XIAO-XIONG, GE, JIAN-WEI, WANG, GUI-SONG, XIONG, WEN-HAO, GUO, PIN, QIU, YONG-MING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626131/
https://www.ncbi.nlm.nih.gov/pubmed/26324126
http://dx.doi.org/10.3892/mmr.2015.4241