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Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1α/PPARα-FGF21 signaling pathway in male Sprague Dawley rats undergoing catch-up growth

The present study investigated the effects of Astragalus polysaccharides (APS) on insulin resistance by modulation of hepatic sirtuin 1 (SIRT1)-peroxisome proliferator-activated receptor (PPAR)-γ coactivator (PGC)-1α/PPARα-fibroblast growth factor (FGF)21, and glucose and lipid metabolism. Thirty ma...

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Detalles Bibliográficos
Autores principales:	GU, CHENGYING, ZENG, YIPENG, TANG, ZHAOSHENG, WANG, CHAOXUN, HE, YANJU, FENG, XINGE, ZHOU, LIGANG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626146/ https://www.ncbi.nlm.nih.gov/pubmed/26323321 http://dx.doi.org/10.3892/mmr.2015.4245

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