Abnormal alterations in the Ca(2+)/CaV1.2/calmodulin/caMKII signaling pathway in a tremor rat model and in cultured hippocampal neurons exposed to Mg(2+)-free solution

Voltage-dependent calcium channels (VDCCs) are key elements in epileptogenesis. There are several binding-sites linked to calmodulin (CaM) and several potential CaM-dependent protein kinase II (CaMKII)-mediated phosphorylation sites in CaV1.2. The tremor rat model (TRM) exhibits absence-like seizure...

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Detalles Bibliográficos
Autores principales: LV, XINTONG, GUO, FENG, XU, XIAOXUE, CHEN, ZAIXING, SUN, XUEFEI, MIN, DONGYU, CAO, YONGGANG, SHI, XIANBAO, WANG, LEI, CHEN, TIANBAO, SHAW, CHRIS, GAO, HUILING, HAO, LIYING, CAI, JIQUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626152/
https://www.ncbi.nlm.nih.gov/pubmed/26299765
http://dx.doi.org/10.3892/mmr.2015.4227

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