4-Hydroxyisoleucine improves insulin resistance in HepG2 cells by decreasing TNF-α and regulating the expression of insulin signal transduction proteins

Previous studies have indicated that 4-hydroxy-isoleucine (4-HIL) improves insulin resistance, however, the underlying mechanisms remain to be elucidated. In the present study, the molecular mechanisms underlying how 4-HIL improves insulin resistance in hepatocytes were examined. HepG2 cells were co...

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Detalles Bibliográficos
Autores principales: GAO, FENG, JIAN, LIUMENG, ZAFAR, MOHAMMAD ISHRAQ, DU, WEN, CAI, QIN, SHAFQAT, RAJA ADEEL, LU, FURONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626171/
https://www.ncbi.nlm.nih.gov/pubmed/26352439
http://dx.doi.org/10.3892/mmr.2015.4298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626171/
https://www.ncbi.nlm.nih.gov/pubmed/26352439
http://dx.doi.org/10.3892/mmr.2015.4298

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