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Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms

Chronic lymphocytic leukemia (CLL) is the most common type of adult leukemia, and is currently incurable due to drug resistance. A previous study indicated that the redox interaction between bone marrow stromal cells and leukemia cells profoundly affected CLL cell viability and drug response. The pr...

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Detalles Bibliográficos
Autores principales: ZHANG, WAN, PELICANO, HELENE, YIN, RAN, ZENG, JUNYI, WEN, TONG, DING, LU, HUANG, RUIBIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626185/
https://www.ncbi.nlm.nih.gov/pubmed/26458979
http://dx.doi.org/10.3892/mmr.2015.4364