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The Trigger Factor Chaperone Encapsulates and Stabilizes Partial Folds of Substrate Proteins
How chaperones interact with protein chains to assist in their folding is a central open question in biology. Obtaining atomistic insight is challenging in particular, given the transient nature of the chaperone-substrate complexes and the large system sizes. Recent single-molecule experiments have...
Autores principales: | Singhal, Kushagra, Vreede, Jocelyne, Mashaghi, Alireza, Tans, Sander J., Bolhuis, Peter G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626277/ https://www.ncbi.nlm.nih.gov/pubmed/26512985 http://dx.doi.org/10.1371/journal.pcbi.1004444 |
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