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Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation
We carried out an integrative analysis of enhancer landscape and gene expression dynamics in hematopoietic differentiation using DNase-seq, histone mark ChIP-seq, and RNA-seq to model how early establishment of enhancers and regulatory locus complexity govern gene expression changes at cell state tr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626279/ https://www.ncbi.nlm.nih.gov/pubmed/26390058 http://dx.doi.org/10.1038/ng.3402 |