The Genomic Landscape of Juvenile Myelomonocytic Leukemia

Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm (MPN) of childhood with a poor prognosis. Mutations in NF1, NRAS, KRAS, PTPN11 and CBL occur in 85% of patients, yet there are currently no risk stratification algorithms capable of predicting which patients will be refractory...

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Detalles Bibliográficos
Autores principales: Stieglitz, Elliot, Taylor-Weiner, Amaro N., Chang, Tiffany Y., Gelston, Laura C., Wang, Yong-Dong, Mazor, Tali, Esquivel, Emilio, Yu, Ariel, Seepo, Sara, Olsen, Scott, Rosenberg, Mara, Archambeault, Sophie L., Abusin, Ghada, Beckman, Kyle, Brown, Patrick A., Briones, Michael, Carcamo, Benjamin, Cooper, Todd, Dahl, Gary V., Emanuel, Peter D., Fluchel, Mark N., Goyal, Rakesh K., Hayashi, Robert J., Hitzler, Johann, Hugge, Christopher, Liu, Y. Lucy, Messinger, Yoav H., Mahoney, Donald H., Monteleone, Philip, Nemecek, Eneida R., Roehrs, Philip A., Schore, Reuven J., Stine, Kimo C., Takemoto, Clifford M., Toretsky, Jeffrey A., Costello, Joseph F., Olshen, Adam B., Stewart, Chip, Li, Yongjin, Ma, Jing, Gerbing, Robert B., Alonzo, Todd A., Getz, Gad, Gruber, Tanja, Golub, Todd, Stegmaier, Kimberly, Loh, Mignon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626387/
https://www.ncbi.nlm.nih.gov/pubmed/26457647
http://dx.doi.org/10.1038/ng.3400

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