Fatal Toxoplasma gondii infection in the giant panda

Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and...

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Detalles Bibliográficos
Autores principales: Ma, Hongyu, Wang, Zedong, Wang, Chengdong, Li, Caiwu, Wei, Feng, Liu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2015
Materias:
Short Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626621/
https://www.ncbi.nlm.nih.gov/pubmed/26514595
http://dx.doi.org/10.1051/parasite/2015030
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author Ma, Hongyu
Wang, Zedong
Wang, Chengdong
Li, Caiwu
Wei, Feng
Liu, Quan
author_facet Ma, Hongyu
Wang, Zedong
Wang, Chengdong
Li, Caiwu
Wei, Feng
Liu, Quan
author_sort Ma, Hongyu
collection PubMed
description Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci, clonal type II at the SAG2, BTUB, GRA6, c22-8, and L358 loci, and clonal type III at the alternative SAG2 and SAG3 loci, thus, a potential new genotype of T. gondii in the giant panda. Other possible pathogens were not detected. To our knowledge, this is the first report of clinical toxoplasmosis in a giant panda.
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spelling pubmed-46266212015-11-24 Fatal Toxoplasma gondii infection in the giant panda Ma, Hongyu Wang, Zedong Wang, Chengdong Li, Caiwu Wei, Feng Liu, Quan Parasite Short Note Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci, clonal type II at the SAG2, BTUB, GRA6, c22-8, and L358 loci, and clonal type III at the alternative SAG2 and SAG3 loci, thus, a potential new genotype of T. gondii in the giant panda. Other possible pathogens were not detected. To our knowledge, this is the first report of clinical toxoplasmosis in a giant panda. EDP Sciences 2015 2015-10-29 /pmc/articles/PMC4626621/ /pubmed/26514595 http://dx.doi.org/10.1051/parasite/2015030 Text en © H. Ma et al., published by EDP Sciences, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Note
Ma, Hongyu
Wang, Zedong
Wang, Chengdong
Li, Caiwu
Wei, Feng
Liu, Quan
Fatal Toxoplasma gondii infection in the giant panda
title Fatal Toxoplasma gondii infection in the giant panda
title_full Fatal Toxoplasma gondii infection in the giant panda
title_fullStr Fatal Toxoplasma gondii infection in the giant panda
title_full_unstemmed Fatal Toxoplasma gondii infection in the giant panda
title_short Fatal Toxoplasma gondii infection in the giant panda
title_sort fatal toxoplasma gondii infection in the giant panda
topic Short Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626621/
https://www.ncbi.nlm.nih.gov/pubmed/26514595
http://dx.doi.org/10.1051/parasite/2015030
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AT licaiwu fataltoxoplasmagondiiinfectioninthegiantpanda
AT weifeng fataltoxoplasmagondiiinfectioninthegiantpanda
AT liuquan fataltoxoplasmagondiiinfectioninthegiantpanda

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