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The Akt-mTOR axis is a pivotal regulator of eccentric hypertrophy during volume overload

The heart has two major modalities of hypertrophy in response to hemodynamic loads: concentric and eccentric hypertrophy caused by pressure and volume overload (VO), respectively. However, the molecular mechanism of eccentric hypertrophy remains poorly understood. Here we demonstrate that the Akt-ma...

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Detalles Bibliográficos
Autores principales:	Ikeda, Masataka, Ide, Tomomi, Fujino, Takeo, Matsuo, Yuka, Arai, Shinobu, Saku, Keita, Kakino, Takamori, Oga, Yasuhiro, Nishizaki, Akiko, Sunagawa, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626834/ https://www.ncbi.nlm.nih.gov/pubmed/26515499 http://dx.doi.org/10.1038/srep15881

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