Aubergine iCLIP Reveals piRNA-Dependent Decay of mRNAs Involved in Germ Cell Development in the Early Embryo

The Piwi-interacting RNA (piRNA) pathway plays an essential role in the repression of transposons in the germline. Other functions of piRNAs such as post-transcriptional regulation of mRNAs are now emerging. Here, we perform iCLIP with the PIWI protein Aubergine (Aub) and identify hundreds of matern...

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Detalles Bibliográficos
Autores principales: Barckmann, Bridlin, Pierson, Stéphanie, Dufourt, Jérémy, Papin, Catherine, Armenise, Claudia, Port, Fillip, Grentzinger, Thomas, Chambeyron, Séverine, Baronian, Grégory, Desvignes, Jean-Pierre, Curk, Tomaz, Simonelig, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626872/
https://www.ncbi.nlm.nih.gov/pubmed/26257181
http://dx.doi.org/10.1016/j.celrep.2015.07.030

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