The Essential Role of Cholesterol Metabolism in the Intracellular Survival of Mycobacterium leprae Is Not Coupled to Central Carbon Metabolism and Energy Production

Mycobacterium leprae induces the formation of lipid droplets, which are recruited to pathogen-containing phagosomes in infected macrophages and Schwann cells. Cholesterol is among the lipids with increased abundance in M. leprae-infected cells, and intracellular survival relies on cholesterol accumu...

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Detalles Bibliográficos
Autores principales: Marques, Maria Angela M., Berrêdo-Pinho, Marcia, Rosa, Thabatta L. S. A., Pujari, Venugopal, Lemes, Robertha M. R., Lery, Leticia M. S., Silva, Carlos Adriano M., Guimarães, Ana Carolina R., Atella, Georgia C., Wheat, William H., Brennan, Patrick J., Crick, Dean C., Belisle, John T., Pessolani, Maria Cristina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626898/
https://www.ncbi.nlm.nih.gov/pubmed/26391209
http://dx.doi.org/10.1128/JB.00625-15

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