Urinary bladder leiomyosarcoma following radiotherapy in a patient with bilateral retinoblastoma: A case report

Retinoblastoma patients have excellent survival following primary treatment by enucleation, radiotherapy or chemotherapy. Patients receiving chemotherapy or radiotherapy may develop second malignancies years later due to DNA damage or genetic mutations. Urinary bladder leiomyosarcoma is one among th...

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Detalles Bibliográficos
Autores principales: Doddamani, Siddalingeshwar C., Bhat, Suresh, Jacob, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626926/
https://www.ncbi.nlm.nih.gov/pubmed/26604453
http://dx.doi.org/10.4103/0970-1591.166471
Descripción
Sumario:Retinoblastoma patients have excellent survival following primary treatment by enucleation, radiotherapy or chemotherapy. Patients receiving chemotherapy or radiotherapy may develop second malignancies years later due to DNA damage or genetic mutations. Urinary bladder leiomyosarcoma is one among them and most such cases have been reported after chemotherapy. We report the third case occurring after isolated radiotherapy.

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