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Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea

With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period. The study population included 104 mothers and their children pairs w...

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Autores principales: Kim, Yu-Mi, Chung, Jin-Young, An, Hyun Sook, Park, Sung Yong, Kim, Byoung-Gwon, Bae, Jong Woon, Han, Myoungseok, Cho, Yeon Jean, Hong, Young-Seoub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627044/
https://www.ncbi.nlm.nih.gov/pubmed/26516876
http://dx.doi.org/10.3390/ijerph121013482
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author Kim, Yu-Mi
Chung, Jin-Young
An, Hyun Sook
Park, Sung Yong
Kim, Byoung-Gwon
Bae, Jong Woon
Han, Myoungseok
Cho, Yeon Jean
Hong, Young-Seoub
author_facet Kim, Yu-Mi
Chung, Jin-Young
An, Hyun Sook
Park, Sung Yong
Kim, Byoung-Gwon
Bae, Jong Woon
Han, Myoungseok
Cho, Yeon Jean
Hong, Young-Seoub
author_sort Kim, Yu-Mi
collection PubMed
description With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period. The study population included 104 mothers and their children pairs who completed both baseline maternal blood sampling at the second trimester and umbilical cord blood sampling at birth. The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively. The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively. The levels of most heavy metals in pregnant women and infants were higher in this study than in studies from industrialized western countries. The placenta appears to protect fetuses from cadmium; however, total mercury and methylmercury were able to cross the placenta and accumulate in fetuses.
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spelling pubmed-46270442015-11-12 Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea Kim, Yu-Mi Chung, Jin-Young An, Hyun Sook Park, Sung Yong Kim, Byoung-Gwon Bae, Jong Woon Han, Myoungseok Cho, Yeon Jean Hong, Young-Seoub Int J Environ Res Public Health Article With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period. The study population included 104 mothers and their children pairs who completed both baseline maternal blood sampling at the second trimester and umbilical cord blood sampling at birth. The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively. The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively. The levels of most heavy metals in pregnant women and infants were higher in this study than in studies from industrialized western countries. The placenta appears to protect fetuses from cadmium; however, total mercury and methylmercury were able to cross the placenta and accumulate in fetuses. MDPI 2015-10-26 2015-10 /pmc/articles/PMC4627044/ /pubmed/26516876 http://dx.doi.org/10.3390/ijerph121013482 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Yu-Mi
Chung, Jin-Young
An, Hyun Sook
Park, Sung Yong
Kim, Byoung-Gwon
Bae, Jong Woon
Han, Myoungseok
Cho, Yeon Jean
Hong, Young-Seoub
Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
title Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
title_full Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
title_fullStr Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
title_full_unstemmed Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
title_short Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea
title_sort biomonitoring of lead, cadmium, total mercury, and methylmercury levels in maternal blood and in umbilical cord blood at birth in south korea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627044/
https://www.ncbi.nlm.nih.gov/pubmed/26516876
http://dx.doi.org/10.3390/ijerph121013482
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