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Ca(2+) enrichment in culture medium potentiates effect of oligonucleotides

Antisense and RNAi-related oligonucleotides have gained attention as laboratory tools and therapeutic agents based on their ability to manipulate biological events in vitro and in vivo. We show that Ca(2+) enrichment of medium (CEM) potentiates the in vitro activity of multiple types of oligonucleot...

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Detalles Bibliográficos
Autores principales: Hori, Shin-ichiro, Yamamoto, Tsuyoshi, Waki, Reiko, Wada, Shunsuke, Wada, Fumito, Noda, Mio, Obika, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627064/
https://www.ncbi.nlm.nih.gov/pubmed/26101258
http://dx.doi.org/10.1093/nar/gkv626