Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element

The majority of mitochondrial DNA replication events are terminated prematurely. The nascent DNA remains stably associated with the template, forming a triple-stranded displacement loop (D-loop) structure. However, the function of the D-loop region of the mitochondrial genome remains poorly understo...

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Detalles Bibliográficos
Autores principales: Jemt, Elisabeth, Persson, Örjan, Shi, Yonghong, Mehmedovic, Majda, Uhler, Jay P., Dávila López, Marcela, Freyer, Christoph, Gustafsson, Claes M., Samuelsson, Tore, Falkenberg, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627069/
https://www.ncbi.nlm.nih.gov/pubmed/26253742
http://dx.doi.org/10.1093/nar/gkv804

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