Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein–RNA toxin–antitoxin system

Genes encoding toxin–antitoxin (TA) systems are near ubiquitous in bacterial genomes and they play key roles in important aspects of bacterial physiology, including genomic stability, formation of persister cells under antibiotic stress, and resistance to phage infection. The CptIN locus from Eubact...

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Detalles Bibliográficos
Autores principales: Rao, Feng, Short, Francesca L., Voss, Jarrod E., Blower, Tim R., Orme, Anastasia L., Whittaker, Tom E., Luisi, Ben F., Salmond, George P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627078/
https://www.ncbi.nlm.nih.gov/pubmed/26350213
http://dx.doi.org/10.1093/nar/gkv868

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