MCM ring hexamerization is a prerequisite for DNA-binding

The hexameric Minichromosome Maintenance (MCM) protein complex forms a ring that unwinds DNA at the replication fork in eukaryotes and archaea. Our recent crystal structure of an archaeal MCM N-terminal domain bound to single-stranded DNA (ssDNA) revealed ssDNA associating across tight subunit inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Froelich, Clifford A., Nourse, Amanda, Enemark, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627082/
https://www.ncbi.nlm.nih.gov/pubmed/26365238
http://dx.doi.org/10.1093/nar/gkv914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627082/
https://www.ncbi.nlm.nih.gov/pubmed/26365238
http://dx.doi.org/10.1093/nar/gkv914

Ejemplares similares