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Systematic reconstruction of binding and stability landscapes of the fluorogenic aptamer spinach

Fluorogenic RNAs that are based on the complex formed by 3,5-difluoro-4-hydroxybenzylidene imidazolinone (DFHBI) derivatives and the RNA aptamer named Spinach were used to engineer a new generation of in vitro and in vivo sensors for bioanalytics. With the resolved crystal structure of the RNA/small...

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Detalles Bibliográficos
Autores principales:	Ketterer, Simon, Fuchs, David, Weber, Wilfried, Meier, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627091/ https://www.ncbi.nlm.nih.gov/pubmed/26400180 http://dx.doi.org/10.1093/nar/gkv944

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