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Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats
Generation of the auditory steady state responses (ASSR) is commonly explained by the linear combination of random background noise activity and the stationary response. Based on this model, the decrease of amplitude that occurs over the sequential averaging of epochs of the raw data has been exclus...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627118/ https://www.ncbi.nlm.nih.gov/pubmed/26557360 http://dx.doi.org/10.4081/audiores.2015.113 |
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author | Prado-Gutierrez, Pavel Castro-Fariñas, Anisleidy Morgado-Rodriguez, Lisbet Velarde-Reyes, Ernesto Martínez, Agustín D. Martínez-Montes, Eduardo |
author_facet | Prado-Gutierrez, Pavel Castro-Fariñas, Anisleidy Morgado-Rodriguez, Lisbet Velarde-Reyes, Ernesto Martínez, Agustín D. Martínez-Montes, Eduardo |
author_sort | Prado-Gutierrez, Pavel |
collection | PubMed |
description | Generation of the auditory steady state responses (ASSR) is commonly explained by the linear combination of random background noise activity and the stationary response. Based on this model, the decrease of amplitude that occurs over the sequential averaging of epochs of the raw data has been exclusively linked to the cancelation of noise. Nevertheless, this behavior might also reflect the non-stationary response of the ASSR generators. We tested this hypothesis by characterizing the ASSR time course in rats with different auditory maturational stages. ASSR were evoked by 8-kHz tones of different supra-threshold intensities, modulated in amplitude at 115 Hz. Results show that the ASSR amplitude habituated to the sustained stimulation and that dishabituation occurred when deviant stimuli were presented. ASSR habituation increased as animals became adults, suggesting that the ability to filter acoustic stimuli with no-relevant temporal information increased with age. Results are discussed in terms of the current model of the ASSR generation and analysis procedures. They might have implications for audiometric tests designed to assess hearing in subjects who cannot provide reliable results in the psychophysical trials. |
format | Online Article Text |
id | pubmed-4627118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-46271182015-11-09 Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats Prado-Gutierrez, Pavel Castro-Fariñas, Anisleidy Morgado-Rodriguez, Lisbet Velarde-Reyes, Ernesto Martínez, Agustín D. Martínez-Montes, Eduardo Audiol Res Article Generation of the auditory steady state responses (ASSR) is commonly explained by the linear combination of random background noise activity and the stationary response. Based on this model, the decrease of amplitude that occurs over the sequential averaging of epochs of the raw data has been exclusively linked to the cancelation of noise. Nevertheless, this behavior might also reflect the non-stationary response of the ASSR generators. We tested this hypothesis by characterizing the ASSR time course in rats with different auditory maturational stages. ASSR were evoked by 8-kHz tones of different supra-threshold intensities, modulated in amplitude at 115 Hz. Results show that the ASSR amplitude habituated to the sustained stimulation and that dishabituation occurred when deviant stimuli were presented. ASSR habituation increased as animals became adults, suggesting that the ability to filter acoustic stimuli with no-relevant temporal information increased with age. Results are discussed in terms of the current model of the ASSR generation and analysis procedures. They might have implications for audiometric tests designed to assess hearing in subjects who cannot provide reliable results in the psychophysical trials. PAGEPress Publications, Pavia, Italy 2015-01-21 /pmc/articles/PMC4627118/ /pubmed/26557360 http://dx.doi.org/10.4081/audiores.2015.113 Text en ©Copyright P. Prado-Gutierrez et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Prado-Gutierrez, Pavel Castro-Fariñas, Anisleidy Morgado-Rodriguez, Lisbet Velarde-Reyes, Ernesto Martínez, Agustín D. Martínez-Montes, Eduardo Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats |
title | Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats |
title_full | Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats |
title_fullStr | Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats |
title_full_unstemmed | Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats |
title_short | Habituation of Auditory Steady State Responses Evoked by Amplitude-Modulated Acoustic Signals in Rats |
title_sort | habituation of auditory steady state responses evoked by amplitude-modulated acoustic signals in rats |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627118/ https://www.ncbi.nlm.nih.gov/pubmed/26557360 http://dx.doi.org/10.4081/audiores.2015.113 |
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