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Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis

Anaplastic thyroid cancer (ATC) is rare but it is one of the most lethal human malignancies with no effective therapy. There is a pressing need to identify new therapeutic agents for ATC. We performed quantitative high-throughput screening (qHTS) in ATC cell lines using a compound library of 3,282 d...

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Detalles Bibliográficos
Autores principales:	Sadowski, Samira M., Boufraqech, Myriem, Zhang, Lisa, Mehta, Amit, Kapur, Payal, Zhang, Yaqin, Li, Zhuyin, Shen, Min, Kebebew, Electron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627234/ https://www.ncbi.nlm.nih.gov/pubmed/25945839

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