Loss of ATRX, associated with DNA methylation pattern of chromosome end, impacted biological behaviors of astrocytic tumors

Loss of ATRX leads to epigenetic alterations, including abnormal levels of DNA methylation at repetitive elements such as telomeres in murine cells. We conducted an extensive DNA methylation and mRNA expression profile study on a cohort of 82 patients with astrocytic tumors to study whether ATRX exp...

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Detalles Bibliográficos
Autores principales: Cai, Jinquan, Chen, Jing, Zhang, Wei, Yang, Pei, Zhang, Chuanbao, Li, Mingyang, Yao, Kun, Wang, Hongjun, Li, Qingbin, Jiang, Chuanlu, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627238/
https://www.ncbi.nlm.nih.gov/pubmed/25971279

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