Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer

PURPOSE: We conducted an open-label, single-arm Phase I/II clinical trial in metastatic CRPC (mCRPC) patients eligible for docetaxel combined with treatment with autologous mature dendritic cells (DCs) pulsed with killed LNCaP prostate cancer cells (DCVAC/PCa). The primary and secondary endpoints we...

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Detalles Bibliográficos
Autores principales: Podrazil, Michal, Horvath, Rudolf, Becht, Etienne, Rozkova, Daniela, Bilkova, Pavla, Sochorova, Klara, Hromadkova, Hana, Kayserova, Jana, Vavrova, Katerina, Lastovicka, Jan, Vrabcova, Petra, Kubackova, Katerina, Gasova, Zdenka, Jarolim, Ladislav, Babjuk, Marek, Spisek, Radek, Bartunkova, Jirina, Fucikova, Jitka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627245/
https://www.ncbi.nlm.nih.gov/pubmed/26078335

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