Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis

Inhibitor of differentiation/DNA binding (Id)1 is a crucial regulator of mammary development and breast cancer progression. However, its effect on stemness and tumorigenesis in mammary epithelial cells remains undefined. Herein, we demonstrate that Id1 induces mammary tumorigenesis by increasing nor...

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Detalles Bibliográficos
Autores principales: Shin, Dong-Hui, Park, Ji-Hye, Lee, Jeong-Yeon, Won, Hee-Young, Jang, Ki-Seok, Min, Kyueng-Whan, Jang, Si-Hyong, Woo, Jong-Kyu, Oh, Seung Hyun, Kong, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627307/
https://www.ncbi.nlm.nih.gov/pubmed/25938540

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