TAT-ODD-p53 enhances the radiosensitivity of hypoxic breast cancer cells by inhibiting Parkin-mediated mitophagy

Radiation therapy has an important role in the treatment of breast cancer. Dysfunction p53 and hypoxia are typical biological characteristics of breast cancer that constitute barriers to the efficacy of radiotherapy. Mitophagy plays a protective role in cellular homeostasis under hypoxic conditions,...

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Detalles Bibliográficos
Autores principales: Zheng, Rong, Yao, Qiwei, Xie, Guozhu, Du, Shasha, Ren, Chen, Wang, Yuxia, Yuan, Yawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627318/
https://www.ncbi.nlm.nih.gov/pubmed/26025927

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