Endothelial Rac1 is essential for hematogenous metastasis to the lung

A variety of vasoactive stimuli induce endothelial permeability through Rac1, a membrane of Rho small GTPases. Here, we determine whether tumor-secreted vasoactive stimulant through Rac1 inducing permeability contributes to hematogenous metastasis. Activation of Rac1 was assayed in human umbilical v...

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Detalles Bibliográficos
Autores principales: Yao, Hongyi, Shi, Wei, Wu, Junsong, Xu, Chengyun, Wang, Jirong, Shao, Yanan, Wu, Ximei, Zhang, Zhongmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627324/
https://www.ncbi.nlm.nih.gov/pubmed/25991673

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