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The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma

The vacuolar H(+) ATPase (V-ATPase) is a proton pump responsible for acidification of cellular microenvironments, an activity exploited by tumors to survive, proliferate and resist to therapy. Despite few observations, the role of V-ATPase in human tumorigenesis remains unclear. We investigated the...

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Detalles Bibliográficos
Autores principales: Di Cristofori, Andrea, Ferrero, Stefano, Bertolini, Irene, Gaudioso, Gabriella, Russo, Maria Veronica, Berno, Valeria, Vanini, Marco, Locatelli, Marco, Zavanone, Mario, Rampini, Paolo, Vaccari, Thomas, Caroli, Manuela, Vaira, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627325/
https://www.ncbi.nlm.nih.gov/pubmed/26020805