UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity

The importance of stress-induced p53 activation has been extensively investigated and well established. How the basal activity of p53 prevents carcinogenesis, however, remains incompletely understood. We report the identification of a novel p53 inhibitor, UXT, which binds to MDMX and suppresses the...

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Detalles Bibliográficos
Autores principales: Qi, Min, Ganapathy, Suthakar, Zeng, Weiqi, Zhang, Jianglin, Little, John B., Yuan, Zhi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627330/
https://www.ncbi.nlm.nih.gov/pubmed/25974965

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