Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma

Glioblastomas (GBMs) are deadly tumors of the central nervous system. Most GBM exhibit homozygous deletions of the CDKN2A and CDKN2B tumor suppressors at 9p21.3, although loss of CDKN2A/B alone is insufficient to drive gliomagenesis. MIR31HG, which encodes microRNA-31 (miR-31), is a novel non-coding...

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Detalles Bibliográficos
Autores principales: Rajbhandari, Rajani, McFarland, Braden C., Patel, Ashish, Gerigk, Magda, Gray, G. Kenneth, Fehling, Samuel C., Bredel, Markus, Berbari, Nicolas F., Kim, Hyunsoo, Marks, Margaret P., Meares, Gordon P., Sinha, Tanvi, Chuang, Jeffrey, Benveniste, Etty N., Nozell, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627347/
https://www.ncbi.nlm.nih.gov/pubmed/26164206

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