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Neuroinflammatory paradigms in lysosomal storage diseases
Lysosomal storage diseases (LSDs) include approximately 70 distinct disorders that collectively account for 14% of all inherited metabolic diseases. LSDs are caused by mutations in various enzymes/proteins that disrupt lysosomal function, which impairs macromolecule degradation following endosome-ly...
Autores principales: | Bosch, Megan E., Kielian, Tammy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627351/ https://www.ncbi.nlm.nih.gov/pubmed/26578874 http://dx.doi.org/10.3389/fnins.2015.00417 |
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