Complement inhibition decreases early fibrogenic events in the lung of septic baboons

Acute respiratory distress syndrome (ARDS) induced by severe sepsis can trigger persistent inflammation and fibrosis. We have shown that experimental sepsis in baboons recapitulates ARDS progression in humans, including chronic inflammation and long-lasting fibrosis in the lung. Complement activatio...

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Detalles Bibliográficos
Autores principales: Silasi-Mansat, Robert, Zhu, Hua, Georgescu, Constantin, Popescu, Narcis, Keshari, Ravi S, Peer, Glenn, Lupu, Cristina, Taylor, Fletcher B, Pereira, Heloise Anne, Kinasewitz, Gary, Lambris, John D, Lupu, Florea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627561/
https://www.ncbi.nlm.nih.gov/pubmed/26337158
http://dx.doi.org/10.1111/jcmm.12667

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