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Orally-Induced Intestinal CD4(+) CD25(+) FoxP3(+) Treg Controlled Undesired Responses towards Oral Antigens and Effectively Dampened Food Allergic Reactions
The induction of peripheral tolerance may constitute a disease-modifying treatment for allergic patients. We studied how oral immunotherapy (OIT) with milk proteins controlled allergy in sensitized mice (cholera toxin plus milk proteins) upon exposure to the allergen. Symptoms were alleviated, skin...
Autores principales: | Smaldini, Paola Lorena, Orsini Delgado, María Lucía, Fossati, Carlos Alberto, Docena, Guillermo Horacio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627767/ https://www.ncbi.nlm.nih.gov/pubmed/26517875 http://dx.doi.org/10.1371/journal.pone.0141116 |
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